教室セミナー 2010年
2010年12月20日
| 第１８０回 | 2010/1/4 | 佐藤 | Khristy W. et al. （2009） Changes in GABA(A) receptor subunit gamma 2 in extensor and flexor motoneurons and astrocytes after spinal cord transection and motor training. Brain Res. 1273, 9-17. |
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| 第１８１回 | 2010/1/13 | 垣沼 | Wong SY. et al. （2009） Primary cilia can both mediate and suppress Hedgehog pathway-dependent tumorigenesis. Nat Med. 15(9), 1055-61. |
| 第１８２回 | 2010/1/18 | 吉村 | Verheijen MH. et al. （2009） SCAP is required for timely and proper myelin membrane synthesis. PNAS 106(50), 21383-8. |
| 第１８３回 | 2010/1/25 | 成田 | Stubbs JL. et al. （2008） The forkhead protein Foxj1 specifies node-like cilia in Xenopus and zebrafish embryos. Nat Genet. 40(12), 1454-60. |
| 第１８４回 | 2010/2/1 | 竹田 | ① Delaval B, Doxsey SJ. （2010） Pericentrin in cellular function and disease. J CB. 188(2), 181-90.② Follit JA. et al. （2010） The cytoplasmic tail of fibrocystin contains a ciliary targeting sequence. J CB. 188(1), 21-8. ③ Lechtreck KF. et al. （2009） The Chlamydomonas reinhardtii BBSome is an IFT cargo required for export of specific signaling proteins from flagella. J CB. 187(7), 1117-32. |
| 第１８５回 | 2010/2/9 | 林 | Nalbant P. et al. （2009） Guanine nucleotide exchange factor-H1 regulates cell migration via localized activation of RhoA at the leading edge. Mol Biol Cell. 20(18), 4070-82. |
| 第１８６回 | 2010/2/15 | 関谷 | Aizawa H. et al. （2005） Laterotopic representation of left-right information onto the dorso-ventral axis of a zebrafish midbrain target nucleus. Curr Biol. 15(3), 238-43. |
| 第１８７回 | 2010/2/22 | 三澤 | Dun SL. et al. （2010） Neuronostatin is co-expressed with somatostatin and mobilizes calcium in cultured rat hypothalamic neurons. ience. 166(2), 455-63. |
| 第１８８回 | 2010/3/8 | 田川 | ① Sch_fer KC. et al. （2009） In vivo, in situ tissue analysis using rapid evaporative ionization mass spectrometry. Angew Chem Int Ed Engl. 48(44), 8240-2.② 質量分析とイオン化法の手技と理論の説明 |
| 第１８９回 | 2010/3/15 | 佐藤 | Zhu C. et al. （2009） Cooper-Kuhn C, Kuhn HG, Blomgren K. Age-dependent regenerative responses in the striatum and cortex after hypoxia-ischemia. J Cereb Blood Flow Metab. 29(2), 342-54. |
| 第１９０回 | 2010/3/23 | 三澤、 垣沼、 成田、 吉村、 林 |
日本解剖学会総会の発表予行 |
| 第１９１回 | 2010/4/5 | 垣沼 | Wen X. et al. （2010） Kinetics of hedgehog-dependent full-length Gli3 accumulation in primary cilia and subsequent degradation. Mol Cell Biol. 30(8), 1910-22. |
| 第１９２回 | 2010/4/12 | 吉村 | Nolan-Stevaux O. et al. (2009) GLI1 is regulated through Smoothened-independent mechanisms in neoplastic pancreatic ducts and mediates PDAC cell survival and transformation. Genes Dev. 23(1), 24-36. |
| 第１９３回 | 2010/4/19 | 成田 | Guirao B. et al. (2010) Coupling between hydrodynamic forces and planar cell polarity orients mammalian motile cilia. Nat Cell Biol. 12(4), 341-50. |
| 第１９４回 | 2010/4/26 | 竹田 | ①Sedmak T., Wolfrum U. (2010) Intraflagellar transport molecules in ciliary and nonciliary cells of the retina. J Cell Biol. 189(1), 171-86. ②Engel BD. et al. (2009) Intraflagellar transport particle size scales inversely with flagellar length: revisiting the balance-point length control model. J Cell Biol. 187(1), 81-9. ③Crino PB. (2009) Focal brain malformations: seizures, signaling, sequencing. Epilepsia. Suppl 9, 3-8. |
| 第１９５回 | 2010/5/10 | 関谷 | de Nijs L. et al. (2009) EFHC1 interacts with microtubules to regulate cell division and cortical development. Nat Neurosci. 12(10), 1266-74. |
| 第１９６回 | 2010/5/17 | 笹本 | Florio T. et al. (2003) Somatostatin inhibits tumor angiogenesis and growth via somatostatin receptor-3-mediated regulation of endothelial nitric oxide synthase and mitogen-activated protein kinase activities. Endocrinology. 144(4), 1574-84. |
| 第１９７回 | 2010/5/24 | 垣沼 | Cervantes S. et al. (2010) Primary cilia regulate Gli/Hedgehog activation in pancreas. Proc Natl Acad Sci U S A. 107(22), 10109-14. |
| 第１９８回 | 2010/5/31 | 吉村 | Cotter L. et al. (2010) Dlg1-PTEN interaction regulates myelin thickness to prevent damaging peripheral nerve overmyelination. Science. 328(5984), 1415-8. |
| 第１９９回 | 2010/6/7 | 成田 | Kim J. et al. (2010) Functional genomic screen for modulators of ciliogenesis and cilium length. Nature. 464(7291), 1048-51. |
| 第２００回 | 2010/6/14 | 竹田 | ①Einstein EB. et al. (2010) Somatostatin signaling in neuronal cilia is critical for object recognition memory. J Neurosci. 30(12), 4306-14. ②Griffiths GM. et al. (2010) The immunological synapse: a focal point for endocytosis and exocytosis. J Cell Biol. 189(3), 399-406. |
| 第２０１回 | 2010/6/21 | 関谷 | Christen G.et al. (2010) Pcdp1 is a central apparatus protein that binds Ca2+-calmodulin and regulates ciliary motility. J. Cell Biol. 189(3), 601-612. |
| 第２０２回 | 2010/6/28 | 垣沼 | Schneider L.et al. (2010) Directional cell migration and chemotaxis in wound healing response to PDGF-AA are coordinated by the primary cilium in fibroblasts. Cell Physiol Biochem. 25(2-3), 279-92. |
| 第２０３回 | 2010/7/5 | 笹本 | Barbieri F. et al. (2008) Somatostatin Receptors 1, 2, and 5 Cooperate in the Somatostatin Inhibition of C6 Glioma Cell Proliferation in Vitro via a Phosphotyrosine Phosphatase-{eta}-Dependent Inhibition of Extracellularly Regulated Kinase-1/2. Endocrinology 149, 4736-4746. |
| 第２０４回 | 2010/7/12 | 吉村 | Zbinden M. et al. (2010) NANOG regulates glioma stem cells and is essential in vivo acting in a cross-functional network with GLI1 and p53. EMBO J. 29(15), 2659-74. |
| 第２０５回 | 2010/7/26 | 成田 | Dishinger JF. et al. (2010) Ciliary entry of the kinesin-2 motor KIF17 is regulated by importin-beta2 and RanGTP. Nat Cell Biol. 12(7), 703-10. |
| 第２０６回 | 2010/8/2 | 竹田 | ①Jeong Ho Lee, Joseph G. (2010) The role of primary cilia in neuronal function Gleeson. Neurobiology of Disease 38 167-172. ②Agulhon C. et al. (2010) Hippocampal short- and long-term plasticity are not modulated by astrocyte Ca2+ signaling. Science. 327(5970), 1250-4. ③Li Y. et al1. (2010) The small GTPases ARL-13 and ARL-3 coordinate intraflagellar transport and ciliogenesis.J. C. B. 189(6), 1039-1051. ④Satir1 P. et al. The primary cilium at a glance. (2010) J Cell Sci. 123 (4), 499-503. |
| 第２０７回 | 2010/8/9 | 関谷 | Anja M. et al. (2009) Angiotensin II regulates V2 receptor and pAQP2 during ureteral obstruction. Am J Physiol Renal Physiol 296, 127-134. |
| 第２０８回 | 2010/8/30 | 笹本 | Jin H. et al. (2010) The Conserved Bardet-Biedl Syndrome Proteins Assemble a Coat that Traffics Membrane Proteins to Cilia. Cell 141, 1208-1219. |
| 第２０９回 | 2010/9/6 | 垣沼 | Pratap A. et al. (2010) Inhibition of endogenous hedgehog signaling protects against acute liver injury after ischemia reperfusion. Pharm Res. 27(11), 2492-504. |
| 第２１０回 | 2010/9/13 | 吉村 | Latasa MJ. et al. (2010) Retinoic Acid Regulates Myelin Formation in the Peripheral Nervous System. GLIA 58, 1451-1464. |
| 第２１１回 | 2010/9/21 | 成田 | Craige B. et al. (2010) CEP290 tethers flagellar transition zone microtubules to the membrane and regulates flagellar protein content. J. C. B. 190(5), 927-940. |
| 第２１２回 | 2010/9/27 | 竹田 | ①Kim SK. et al. (2010) Planar Cell Polarity Acts Through Septins to Control Collective Cell Movement and Ciliogenesis. Science. 329(5997), 1337. ②Tull D. et al. (2010) Membrane protein SMP-1 is required for normal flagellum function in Leishmania. J Cell Sci. 123, 544-554. ③Seeley ES. and Nachury MV. (2010) The perennial organelle: assembly and disassembly of the primary cilium J Cell Sci. 123(Pt 4), 511-8. ④Bloodgood RA. (2010) Sensory reception is an attribute of both primary cilia and motile cilia. J Cell Sci. 123(Pt 4), 505-9. ⑤Emmer BT. et al. (2010) Molecular mechanisms of protein and lipid targeting to ciliary membranes. J Cell Sci. 123(Pt 4), 529-36. |
| 第２１３回 | 2010/10/4 | 関谷 | Resnick A. and Hopfer U. (2007) Force-Response Considerations in Ciliary Mechanosensation. Biophysical Biophys J. 93(4), 1380-90. |
| 第２１４回 | 2010/10/12 | 笹本 | Yun HM. et al. (2010) Physical Interaction of Jab1 with Human Serotonin 6 G-protein-coupled Receptor and Their Possible Roles in Cell Survival. J Biol. Chem. 285(13), 10016-10029. |
| 第２１５回 | 2010/10/18 | 垣沼 | Prajerova I. et al. (2010) Distinct effects of sonic hedgehog and Wnt-7a on differentiation of neonatal neural stem/progenitor cells in vitro. Neuroscience. 171(3), 693-711. |
| 第２１６回 | 2010/10/25 | 吉村 | ①Wan. LD. et al. (2010) Electrical stimulation enhanced remyelination of injured sciatic nerves by increasing neurotrophins. Neuroscience. 169(3), 1029-38. ②Rangaraju S. et al. (2010) Rapamycin Activates Autophagy and Improves Myelination in Explant Cultures from Neuropathic Mice. J Neurosci. 30(34), 11388 -11397. |
| 第２１７回 | 2010/11/1 | 成田 | Tissir F. (2010) Lack of cadherins Celsr2 and Celsr3 impairs ependymal ciliogenesis, leading to fatal hydrocephalus. Nat Neurosci. 13(6), 700-7. |
| 第２１８回 | 2010/11/8 | 竹田 | ①Wiczer BM., Kalender A. and Thoma G. (2010) Bending the path to TOR. Nat Cell Biol. 12(11), 1031-3. ②Boehlke C. et al. (2010) Primary cilia regulate mTORC1 activity and cell size through Lkb1. Nat Cell Biol. 12(11), 1115-22. ③Love D. et al. (2010) Altered Lung Morphogenesis, Epithelial Cell Differentiation and Mechanics in Mice Deficient in the Wnt/b-Catenin Antagonist Chibby. PLoS One. 5(10), e13600. |
| 第２１９回 | 2010/11/15 | 関谷 | ①S. Nonaka (2005) De Novo Formation of Left-Right Asymmetry by Posterior Tilt of Nodal Cilia. PLoS Biol. 3(8), e268. ②Smith DJ., Blake JR, Gaffney EA. (2008) Fluid mechanics of nodal flow due to embryonic primary cilia. J R Soc Interface. 5(22), 567-73. |
| 第２２０回 | 2010/11/22 | 笹本 | A. Baudry (2010) MiR-16 Targets the Serotonin Transporter: A New Facet for Adaptive Responses to Antidepressants. Science. 329(5998), 1537-41. |
| 第２２１回 | 2010/11/29 | 垣沼 | Tukachinsky H., Lopez LV., and Salic A. (2010) A mechanism for vertebrate Hedgehog signaling:recruitment to cilia and dissociation of SuFu-Gli protein complexes. J Cell Biol. 191(2), 415-28. |
| 第２２２回 | 2010/12/6 | 吉村 | Yu WM. et al. (2009) Laminin is required for Schwann cell morphogenesis. J Cell Sci. 122(Pt 7), 929-36. |
| 第２２３回 | 2010/12/20 | 成田 | Beckervordersandforth R. et al. (2010) In Vivo Fate Mapping and Expression Analysis Reveals Molecular Hallmarks of Prospectively Isolated Adult Neural Stem Cells. Cell Stem Cell. 7(6), 744-58. |