教室セミナー 2010年


第180回 2010/1/4 佐藤 Khristy W. et al. (2009) Changes in GABA(A) receptor subunit gamma 2 in extensor and flexor motoneurons and astrocytes after spinal cord transection and motor training. Brain Res. 1273, 9-17.
第181回 2010/1/13 垣沼 Wong SY. et al. (2009) Primary cilia can both mediate and suppress Hedgehog pathway-dependent tumorigenesis. Nat Med. 15(9), 1055-61.
第182回 2010/1/18 吉村 Verheijen MH. et al. (2009) SCAP is required for timely and proper myelin membrane synthesis. PNAS 106(50), 21383-8.
第183回 2010/1/25 成田 Stubbs JL. et al. (2008) The forkhead protein Foxj1 specifies node-like cilia in Xenopus and zebrafish embryos. Nat Genet. 40(12), 1454-60.
第184回 2010/2/1 竹田 ① Delaval B, Doxsey SJ. (2010) Pericentrin in cellular function and disease. J CB. 188(2), 181-90.② Follit JA. et al. (2010) The cytoplasmic tail of fibrocystin contains a ciliary targeting sequence. J CB. 188(1), 21-8. ③ Lechtreck KF. et al. (2009) The Chlamydomonas reinhardtii BBSome is an IFT cargo required for export of specific signaling proteins from flagella. J CB. 187(7), 1117-32.
第185回 2010/2/9 Nalbant P. et al. (2009) Guanine nucleotide exchange factor-H1 regulates cell migration via localized activation of RhoA at the leading edge. Mol Biol Cell. 20(18), 4070-82.
第186回 2010/2/15 関谷 Aizawa H. et al. (2005) Laterotopic representation of left-right information onto the dorso-ventral axis of a zebrafish midbrain target nucleus. Curr Biol. 15(3), 238-43.
第187回 2010/2/22 三澤 Dun SL. et al. (2010) Neuronostatin is co-expressed with somatostatin and mobilizes calcium in cultured rat hypothalamic neurons. ience. 166(2), 455-63.
第188回 2010/3/8 田川 ① Sch_fer KC. et al. (2009) In vivo, in situ tissue analysis using rapid evaporative ionization mass spectrometry. Angew Chem Int Ed Engl. 48(44), 8240-2.② 質量分析とイオン化法の手技と理論の説明
第189回 2010/3/15 佐藤 Zhu C. et al. (2009) Cooper-Kuhn C, Kuhn HG, Blomgren K. Age-dependent regenerative responses in the striatum and cortex after hypoxia-ischemia. J Cereb Blood Flow Metab. 29(2), 342-54.
第190回 2010/3/23 三澤、
第191回 2010/4/5 垣沼 Wen X. et al. (2010) Kinetics of hedgehog-dependent full-length Gli3 accumulation in primary cilia and subsequent degradation.  Mol Cell Biol. 30(8), 1910-22.
第192回 2010/4/12 吉村 Nolan-Stevaux O. et al. (2009) GLI1 is regulated through Smoothened-independent mechanisms in neoplastic pancreatic ducts and mediates PDAC cell survival and transformation. Genes Dev. 23(1), 24-36.
第193回 2010/4/19 成田 Guirao B. et al. (2010) Coupling between hydrodynamic forces and planar cell polarity orients mammalian motile cilia. Nat Cell Biol. 12(4), 341-50.
第194回 2010/4/26 竹田 ①Sedmak T., Wolfrum U. (2010) Intraflagellar transport molecules in ciliary and nonciliary cells of the retina. J Cell Biol. 189(1), 171-86.
②Engel BD. et al. (2009) Intraflagellar transport particle size scales inversely with flagellar length: revisiting the balance-point length control model. J Cell Biol. 187(1), 81-9.
③Crino PB. (2009) Focal brain malformations: seizures, signaling, sequencing. Epilepsia. Suppl 9, 3-8.
第195回 2010/5/10 関谷 de Nijs L. et al. (2009) EFHC1 interacts with microtubules to regulate cell division and cortical development. Nat Neurosci. 12(10), 1266-74.
第196回 2010/5/17 笹本 Florio T. et al. (2003) Somatostatin inhibits tumor angiogenesis and growth via somatostatin receptor-3-mediated regulation of endothelial nitric oxide synthase and mitogen-activated protein kinase activities. Endocrinology. 144(4), 1574-84.
第197回 2010/5/24 垣沼 Cervantes S. et al. (2010) Primary cilia regulate Gli/Hedgehog activation in pancreas. Proc Natl Acad Sci U S A. 107(22), 10109-14.
第198回 2010/5/31 吉村 Cotter L. et al. (2010) Dlg1-PTEN interaction regulates myelin thickness to prevent damaging peripheral nerve overmyelination. Science. 328(5984), 1415-8.
第199回 2010/6/7 成田 Kim J. et al. (2010) Functional genomic screen for modulators of ciliogenesis and cilium length. Nature. 464(7291), 1048-51.
第200回 2010/6/14 竹田 ①Einstein EB. et al. (2010) Somatostatin signaling in neuronal cilia is critical for object recognition memory. J Neurosci. 30(12), 4306-14.
②Griffiths GM. et al. (2010) The immunological synapse: a focal point for endocytosis and exocytosis. J Cell Biol. 189(3), 399-406.
第201回 2010/6/21 関谷 Christen G.et al. (2010) Pcdp1 is a central apparatus protein that binds
Ca2+-calmodulin and regulates ciliary motility. J. Cell Biol. 189(3), 601-612.
第202回 2010/6/28 垣沼 Schneider L.et al. (2010) Directional cell migration and chemotaxis in wound healing response to PDGF-AA are coordinated by the primary cilium in fibroblasts. Cell Physiol Biochem. 25(2-3), 279-92.
第203回 2010/7/5 笹本 Barbieri F. et al. (2008) Somatostatin Receptors 1, 2, and 5 Cooperate in the Somatostatin Inhibition of C6 Glioma Cell Proliferation in Vitro via a Phosphotyrosine Phosphatase-{eta}-Dependent Inhibition of Extracellularly Regulated Kinase-1/2. Endocrinology 149, 4736-4746.
第204回 2010/7/12 吉村 Zbinden M. et al. (2010) NANOG regulates glioma stem cells and is essential in vivo acting in a cross-functional network with GLI1 and p53. EMBO J. 29(15), 2659-74.
第205回 2010/7/26 成田 Dishinger JF. et al. (2010) Ciliary entry of the kinesin-2 motor KIF17 is regulated by importin-beta2 and RanGTP. Nat Cell Biol. 12(7), 703-10.
第206回 2010/8/2 竹田 ①Jeong Ho Lee, Joseph G. (2010) The role of primary cilia in neuronal function Gleeson. Neurobiology of Disease 38 167-172.
②Agulhon C. et al. (2010) Hippocampal short- and long-term plasticity are not modulated by astrocyte Ca2+ signaling. Science. 327(5970), 1250-4.
③Li Y. et al1. (2010) The small GTPases ARL-13 and ARL-3 coordinate
intraflagellar transport and ciliogenesis.J. C. B. 189(6), 1039-1051.
④Satir1 P. et al. The primary cilium at a glance. (2010) J Cell Sci. 123 (4), 499-503.
第207回 2010/8/9 関谷 Anja M. et al. (2009) Angiotensin II regulates V2 receptor and pAQP2 during ureteral obstruction. Am J Physiol Renal Physiol 296, 127-134.
第208回 2010/8/30 笹本 Jin H. et al. (2010) The Conserved Bardet-Biedl Syndrome Proteins Assemble a Coat that Traffics Membrane Proteins to Cilia. Cell 141, 1208-1219.
第209回 2010/9/6 垣沼 Pratap A. et al. (2010) Inhibition of endogenous hedgehog signaling protects against acute liver injury after ischemia reperfusion. Pharm Res. 27(11), 2492-504.
第210回 2010/9/13 吉村 Latasa MJ. et al. (2010) Retinoic Acid Regulates Myelin Formation in the Peripheral Nervous System. GLIA 58, 1451-1464.
第211回 2010/9/21 成田 Craige B. et al. (2010) CEP290 tethers flagellar transition zone microtubules to the membrane and regulates flagellar protein content. J. C. B. 190(5), 927-940.
第212回 2010/9/27 竹田 ①Kim SK. et al. (2010) Planar Cell Polarity Acts Through Septins to Control Collective Cell Movement and Ciliogenesis. Science. 329(5997), 1337.
②Tull D. et al. (2010) Membrane protein SMP-1 is required for normal flagellum function in Leishmania. J Cell Sci. 123, 544-554.
③Seeley ES. and Nachury MV. (2010) The perennial organelle: assembly and disassembly of the primary cilium J Cell Sci. 123(Pt 4), 511-8.
④Bloodgood RA. (2010) Sensory reception is an attribute of both primary cilia and motile cilia. J Cell Sci. 123(Pt 4), 505-9.
⑤Emmer BT. et al. (2010) Molecular mechanisms of protein and lipid targeting to ciliary membranes. J Cell Sci. 123(Pt 4), 529-36.
第213回 2010/10/4 関谷 Resnick A. and Hopfer U. (2007) Force-Response Considerations in Ciliary Mechanosensation. Biophysical Biophys J. 93(4), 1380-90.
第214回 2010/10/12 笹本 Yun HM. et al. (2010) Physical Interaction of Jab1 with Human Serotonin 6 G-protein-coupled Receptor and Their Possible Roles in Cell Survival.
J Biol. Chem. 285(13), 10016-10029.
第215回 2010/10/18 垣沼 Prajerova I. et al. (2010) Distinct effects of sonic hedgehog and Wnt-7a on differentiation of neonatal neural stem/progenitor cells in vitro. Neuroscience. 171(3), 693-711.
第216回 2010/10/25 吉村 ①Wan. LD. et al. (2010) Electrical stimulation enhanced remyelination of injured sciatic nerves by increasing neurotrophins. Neuroscience. 169(3), 1029-38.
②Rangaraju S. et al. (2010) Rapamycin Activates Autophagy and Improves Myelination in Explant Cultures from Neuropathic Mice. J Neurosci. 30(34), 11388 -11397.
第217回 2010/11/1 成田 Tissir F. (2010) Lack of cadherins Celsr2 and Celsr3 impairs ependymal ciliogenesis, leading to fatal hydrocephalus. Nat Neurosci. 13(6), 700-7.
第218回 2010/11/8 竹田 ①Wiczer BM., Kalender A. and Thoma G. (2010) Bending the path to TOR. Nat Cell Biol. 12(11), 1031-3.
②Boehlke C. et al. (2010) Primary cilia regulate mTORC1 activity and cell size through Lkb1. Nat Cell Biol. 12(11), 1115-22.
③Love D. et al. (2010) Altered Lung Morphogenesis, Epithelial Cell Differentiation and Mechanics in Mice Deficient in the Wnt/b-Catenin Antagonist Chibby. PLoS One. 5(10), e13600.
第219回 2010/11/15 関谷 ①S. Nonaka (2005) De Novo Formation of Left-Right Asymmetry by Posterior Tilt of Nodal Cilia. PLoS Biol. 3(8), e268.
②Smith DJ., Blake JR, Gaffney EA. (2008) Fluid mechanics of nodal flow due to embryonic primary cilia. J R Soc Interface. 5(22), 567-73.
第220回 2010/11/22 笹本 A. Baudry (2010) MiR-16 Targets the Serotonin Transporter: A New Facet for Adaptive Responses to Antidepressants. Science. 329(5998), 1537-41.
第221回 2010/11/29 垣沼 Tukachinsky H., Lopez LV., and Salic A. (2010) A mechanism for vertebrate Hedgehog signaling:recruitment to cilia and dissociation of SuFu-Gli protein complexes. J Cell Biol. 191(2), 415-28.
第222回 2010/12/6 吉村 Yu WM. et al. (2009) Laminin is required for Schwann cell morphogenesis. J Cell Sci. 122(Pt 7), 929-36.
第223回 2010/12/20 成田 Beckervordersandforth R. et al. (2010) In Vivo Fate Mapping and Expression Analysis Reveals Molecular Hallmarks of Prospectively Isolated Adult Neural Stem Cells. Cell Stem Cell. 7(6), 744-58.