教室セミナー 2017年


第491回 2017/01/04 河原 Gregory Mazo, et al. (2016) Spatial Control of Primary Ciliogenesis by Subdistal Appendages Alters Sensation-Associated Properties of Cilia. Dev Cell. 39(4):424-437.
第492回 2017/01/10 城野 Darren J. Baker, et al. (2016) Naturally occurring p16Ink4a-positive cells shorten healthy lifespan. Nature. 530(7589):184-9.
第493回 2017/01/18 久冨 Kathy E. O’Neill, et al. (2016) Foxn1 Is Dynamically Regulated in Thymic Epithelial Cells during Embryogenesis and at the Onset of Thymic Involution. PLoS One. 11(3):e0151666.
第494回 2017/1/24 岩野 Violeta Silva-Vargas, et al. (2016) Age-Dependent Niche Signals from the Choroid Plexus Regulate Adult Neural Stem Cells. Cell Stem Cell. 19(5):643-652.
第495回 2017/2/1 吉村 Tsutomu Matsubara, et al. (2011) Lithocholic acid disrupts phospholipid and sphingolipid homeostasis leading to cholestasis. Hepatology. 53(4):1282-93.
第496回 2017/2/7 成田 ①Zhengang Zhang, et al. (2016) Intraflagellar transport protein IFT20 is essential for male fertility and spermiogenesis in mice. Mol Biol Cell. pii: mbc.E16-05-0318.

②Jovenal T. et al. (2015) Intraflagellar transport is essential for mammalian spermiogenesis but is absent in mature sperm. Mol Biol Cell. 26(24):4358-72.

第497回 2017/2/14 竹田 Philippe Foerster , et al. (2017) mTORC1 signaling and primary cilia are required for brain ventricle morphogenesis. Development. 144(2):201-210.
第498回 2017/2/21 Xin Wang, et al. (2016) SNX27 Deletion Causes Hydrocephalus by Impairing Ependymal Cell Differentiation and Ciliogenesis. J Neurosci. 36(50):12586-12597.
第499回 2017/2/28 社本 Marina Weidemann , et al. (2016) CFAP157 is a murine downstream effector of FOXJ1 that is specifically required for flagellum morphogenesis and sperm motility. Development. 143(24):4736-4748.
第500回 2017/3/7 中嶋 Yukio Sato, et al. (2016) Notch2 Signaling Regulates the Proliferation of Murine Bone Marrow-Derived Mesenchymal Stem/Stromal Cells via c-Myc Expression. PLoS One. 11(11):e0165946.
第501回 2017/3/14 外国人留学生等研究発表会予行
第502回 2017/3/22 久冨+解剖学会総会発表予行 Ching-In Lau, et al. (2017) The kinesin motor protein Kif7 is required for T-cell development and normal MHC expression on thymic epithelial cells (TEC) in the thymus. Oncotarget. 8(15):24163-24176.
第503回 2017/4/5 河原 Siew Cheng Phua, et al. (2017) Dynamic Remodeling of Membrane Composition Drives Cell Cycle through Primary Cilia Excision. Cell. 168(1-2):264-279.e15.
第504回 2017/4/11 岩野 Ana Pardo-Saganta, et al. (2015) Parent stem cells can serve as niches for their daughter cells. Nature. 523(7562):597-601.
第505回 2017/4/18 吉村 Kenji Chamoto, et al. (2017) Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity. Proc Natl Acad Sci U S A. 114(5):E761-E770.
第506回 2017/4/26 成田 Yujian Wu , et al. (2016) Transcription Factor RFX2 Is a Key Regulator of Mouse Spermiogenesis. Sci Rep. Feb 8;6:20435.
第507回 2017/5/16 竹田 Giorgia Quadrato, et al. (2017) Cell diversity and network dynamics in photosensitive human brain organoids. Nature. 545(7652):48-53.
第508回 2017/5/22 Janos Tözser, .et al. (2015) TGF-b Signaling Regulates the Differentiation of Motile Cilia. Cell Rep. 11(7):1000-7.
第509回 2017/6/5 社本 Anja Feldner, et al. (2017) Loss of Mpdz impairs ependymal cell integrity leading to perinatal-onset hydrocephalus in mice. EMBO Mol Med. May 12. pii: e201606430.
第510回 2017/6/20 河原 Shoko Abe, et al. (2017) Localization of Protein Kinase NDR2 to Peroxisomes and Its Role in Ciliogenesis. J Biol Chem. 292(10):4089-4098.
第511回 2017/6/27 久冨 Jia C. Wang, et al. (2017) The Rap1–cofilin-1 pathway coordinates actin reorganization and MTOC polarization at the B cell immune synapse. J Cell Sci. 130(6):1094-1109.
第512回 2017/7/11 岩野 ①Kiet Hua and Russell J. Ferland (2017) Fixation methods can differentially affect ciliary protein immunolabeling. Cilia. 6:5. doi: 10.1186/s13630-017-0045-9.

②Alejandro Burga, et al. (2017) A genetic signature of the evolution of loss of flight in the Galapagos cormorant. Science. 356(6341). pii: eaal3345.

第513回 2017/7/18 吉村 Andreas P. Dahlin, et al. (2014) Refined Microdialysis Method for Protein Biomarker Sampling in Acute Brain Injury in the Neurointensive Care Setting. Anal Chem. 86(17):8671-9.
第514回 2017/7/26 成田 Daniel Kopinke, Elle C. Roberson, Jeremy F. Reiter (2017) Ciliary Hedgehog Signaling Restricts Injury-Induced Adipogenesis. Cell. 170(2):340-351.
第515回 2017/8/2 竹田 ①Priyanka Kohli, et al. (2017) The ciliary membrane-associated proteome reveals actin-binding proteins as key components of cilia. EMBO Rep. Jul 14. pii: e201643846.

②Xiang Liu, et al. (2017) The Role of the Notch Signal Pathway in Mucosal Cell Metaplasia in Mouse Acute Otitis Media. Sci Rep. 7(1):4588. doi: 10.1038/s41598-017-04639-z.

第516回 2017/8/9 Peter Walentek, et al. (2016) Ciliary transcription factors and miRNAs precisely regulate Cp110 levels required for ciliary adhesions and ciliogenesis. Elife. Sep 13;5. pii: e17557. doi: 10.7554/eLife.17557.
第517回 2017/8/22 社本 Shinsuke Niwa (2016) The nephronophthisis-related gene ift-139 is required for ciliogenesis in Caenorhabditis elegans. Sci Rep. Aug 12;6:31544. doi: 10.1038/srep31544.
第518回 2017/9/5 久冨 Benjamin M. Hariri, et al. (2017) Flavones modulate respiratory epithelial innate immunity: Anti-inflammatory effects and activation of the T2R14 receptor. J Biol Chem. 292(20):8484-8497.
第519回 2017/9/12 河原 Jacob B. Burnett, et al. (2017) Proper ciliary assembly is critical for restricting Hedgehog signaling during early eye development in mice. Dev Biol. 430(1):32-40.
第520回 2017/9/20 岩野 S. Lugert, et al.( 2017) Glypican-2 levels in cerebrospinal fluid predict the status of adult hippocampal neurogenesis. Sci Rep. Apr 25;7:46543.
第521回 2017/10/3 吉村 Marco Urbini et al. (2017) ToF-SIMS and principal component analysis of lipids and amino acids from inflamed and dysplastic human colonic mucosa. Anal Bioanal Chem. Aug 3. doi: 10.1007/s00216-017-0546-9.
第522回 2017/10/11 成田 Maki Takagishi, et al. (2017) Daple Coordinates Planar Polarized Microtubule Dynamics in Ependymal Cells and Contributes to Hydrocephalus. Cell Rep. 20(4):960-972.
第523回 2017/10/17 竹田 ①Premkumar Vummidi Giridhar, et al. (2016) Airway Epithelial KIF3A Regulates Th2 Responses to Aeroallergens. J Immunol. 197(11):4228-4239.

②Matthieu Raveau, et al. (2017) Brain ventriculomegaly in Down syndrome mice is caused by Pcp4 dose-dependent cilia dysfunction. Hum Mol Genet. 26(5):923-931.

第524回 2017/10/24 Matteo Villa1, et al. (2016) The aryl hydrocarbon receptor controls cyclin O to promote epithelial multiciliogenesis. Nat Commun. Aug 24;7:12652. doi: 10.1038/ncomms12652.
第525回 2017/10/31 社本 Xue Jiang, et al. (2017) IFT57 stabilizes the assembled intraflagellar transport complex and mediates transport of motility-related flagellar cargo. J Cell Sci. 130(5):879-891.
第526回 2017/11/6 河原 Kasturi Roy, et al. (2017) Palmitoylation of the ciliary GTPase ARL13b is necessary for its stability and its role in cilia formation. J Biol Chem. 292(43):17703-17717.
第527回 2017/11/15 久冨 ①Hyunjung Baek, et al. (2017) Primary cilia modulate TLR4-mediated inflammatory responses in hippocampal neurons. J Neuroinflammation. 14(1):189. doi: 10.1186/s12974-017-0958-7.

②Mieke Boon , et al. (2014) Primary ciliary dyskinesia and humoral immunodeficiency – Is there a missing link? Respir Med. 108(6):931-4.

第528回 2017/11/21 岩野 Ken Takizawa, et al. (2017) The Choroid Plexus of the Lateral Ventricle As the Origin of CSF Pulsation Is Questionable. Neurol Med Chir (Tokyo). Nov 16. doi: 10.2176/nmc.oa.2017-0117.

②Shalabh Srivastava, et al. (2017) A human patient-derived cellular model of Joubert syndrome reveals ciliary defects which can be rescued with targeted therapies. Hum Mol Genet. 26(23):4657-4667.

第529回 2017/11/29 吉村 Sensen Shen, et al. (2017) A plasma lipidomics strategy reveals perturbed lipid metabolic pathways and potential lipid biomarkers of human colorectal cancer. J Chromatogr B Analyt Technol Biomed Life Sci. 1068-1069:41-48.
第530回 2017/12/12 成田 Hiroko Shimada, et al. (2017) In Vitro Modeling Using Ciliopathy-Patient-Derived Cells Reveals Distinct Cilia Dysfunctions Caused by CEP290 Mutations. Cell Rep. J20(2):384-396.
第531回 2017/12/20 竹田 Hilmarie Muniz-Talavera, Jennifer V. Schmidt (2017) The mouse Jhy gene regulates ependymal cell differentiation and ciliogenesis. PLoS One. 12(12):e0184957.
第532回 2017/12/26 Andreas Schmid, et al. (2017) Modulation of Wnt signaling is essential for the differentiation of ciliated epithelial cells in human airways. FEBS Lett. 591(21):3493-3506.