教室セミナー 2018年



第533回 2018/1/9 河原 Mu He, et al. (2017) Cytoplasmic Cl− couples membrane remodeling to epithelial morphogenesis. Proc Natl Acad Sci U S A. 114(52):E11161-E11169.
第534回 2018/1/16 社本 Stephanie O. Agbu, Yinwen Liang, Aimin Liu, and Kathryn V. Anderson (2018) The small GTPase RSG1 controls a final step in primary cilia initiation. J Cell Biol. 217(1):413-427.
第535回 2018/1/30 久冨 ①Junya Kirima ,Kazuhiro Oiwa (2017) Flagellar-associated protein FAP85 is a microtubule inner protein that stabilizes microtubules. Cell Struct Funct. Dec 28. doi: 10.1247/csf.17023.

②Muneyoshi Ichikawa, et al. (2017) Subnanometre-resolution structure of the doublet M icrotubule reveals new classes of microtubuleassociated proteins. Nat Commun. May 2;8:15035. doi: 10.1038/ncomms15035.

第536回 2018/02/06 岩野 Chien-Ting Wu, Hsin-Yi Chen and Tang K. Tang (2018) Myosin-Va is required for preciliary vesicle transportation to the mother centriole during ciliogenesis. Nat Cell Biol. 20(2):175-185.
第537回 2018/2/14 吉村 Xiaona Li, et al. (2017) LC-MS-based metabolomics revealed SLC25A22 as an essential regulator of aspartate-derived amino acids and polyamines in KRAS-mutant colorectal cancer. Oncotarget. 8(60):101333-101344.
第538回 2018/2/28 成田 Qiaoli Ma, Benjamin V. Ineichen, Michael Detmar & Steven T. Proul (2017) Outflow of cerebrospinal fluid is predominantly through lymphatic vessels and is reduced in aged mice. Nat Commun. 8(1):1434. doi: 10.1038/s41467-017-01484-6.
第539回 2018/3/6 竹田 Michele A. et al. (2018) TRPV4-mediates oscillatory fluid shear mechanotransduction in mesenchymal stem cells in part via the primary cilium. Sci Rep. 8(1):3824. doi: 10.1038/s41598-018-22174-3.
第540回 2018/3/14 Kousuke Kasahara, et al. (2018) EGF receptor kinase suppresses ciliogenesis through activation of USP8 deubiquitinase. Nat Commun. 9(1):758. doi: 10.1038/s41467-018-03117-y.
第541回 2018/03/20 社本 Ulf Hedström, et al. (2018) Bronchial extracellular matrix from COPD patients induces altered gene expression in repopulated primary human bronchial epithelial cells. Sci Rep. 8(1):3502. doi: 10.1038/s41598-018-21727-w.
第542回 2018/04/03 久冨 Charles Coutton et al. (2018) Mutations in CFAP43 and CFAP44 cause male infertility and flagellum defects in Trypanosoma and human. Nat Commun. 9(1):686. doi: 10.1038/s41467-017-02792-7.
第543回 2018/4/11 岩野 Hirahara Y, et al. (2017) Sulfatide species with various fatty acid chains in oligodendrocytes at different developmental stages determined by imaging mass spectrometry. J Neurochem. 140(3):435-450.
第544回 2018/4/18 吉村 Yuki Nagata ,et al. (2018) Comparative analysis of cerebrospinal fluid metabolites in Alzheimer’s disease and idiopathic normal pressure hydrocephalus in a Japanese cohort. Biomark Res. 6:5. doi: 10.1186/s40364-018-0119-x.
第545回 2018/4/24 成田 Kyeong Jee Cho, et al. (2018) ZMYND10 stabilizes intermediate chain proteins in the cytoplasmic pre-assembly of dynein arms. PLoS Genet. 14(3):e1007316.
第546回 2018/5/9 竹田 Anne‑Clémence Vion, et al. (2018) Primary cilia sensitize endothelial cells to BMP and prevent excessive vascular regression. J Cell Biol. 217(5):1651-1665.
第547回 2018/5/16 Zhao Wang, et al. (2018) TRRAP is a central regulator of human multiciliated cell formation. J Cell Biol. pii: jcb.201706106.
第548回 2018/5/22 社本 Alexander Perniss, et al. (2018) Bordetella pseudohinzii targets cilia and impairs tracheal cilia-driven transport in naturally acquired infection in mice. Sci Rep. 8(1):5681.
第549回 2018/05/29 久冨 ①Suzanna L. Prosser and Ciaran G. Morrison (2015) Centrin2 regulates CP110 removal in primary cilium formation. J Cell Biol. 208(6):693-701.

②Mohan Singh, Parvesh Chaudhry, and Akil A. Merchant (2016) Primary cilia are present on human blood and bone marrow cells and mediate Hedgehog signaling. Exp Hematol. 44(12):1181-1187.

第550回 2018/6/12 岩野 ①Marlen Knobloch, et al. (2017) A Fatty Acid Oxidation-Dependent Metabolic Shift Regulates Adult Neural Stem Cell Activity. Cell Rep. 20(9):2144-2155.

②Marlen Knobloch, et al. (2013) Metabolic control of adult neural stemcell activity by Fasn-dependent lipogenesis. Nature. 493(7431):226-30.

第551回 2018/6/19 吉村 Christina H. Stuelten, Rachel M. Lee, Wolfgang Losert, Carole A. Parent (2018) Lysophosphatidic acid regulates the motility of MCF10CA1a breast cancer cell sheets via two opposing signaling pathways. Cell Signal. 45:1-11.
第552回 2018/6/27 成田 Alexia Mahuzier, et al. (2018) Ependymal cilia beating induces an actin network to protect centrioles against shear stress. Nat Commun. 9(1):2279. doi: 10.1038/s41467-018-04676-w.
第553回 2018/7/4 竹田 Andrew D. Jenks, et al (2018) Primary Cilia Mediate Diverse Kinase Inhibitor Resistance Mechanisms in Cancer. Cell Rep. 23(10):3042-3055.
第554回 2018/7/11 Arnab Ghosh, Shafiq M. Syed and Pradeep S. Tanwar (2017) In vivo genetic cell lineage tracing reveals that oviductal secretory cells self-renew and give rise to ciliated cells.Development. 144(17):3031-3041.
第555回 2018/7/18 社本 Michael E. Price, et al. (2018) S-nitrosation of protein

phosphatase 1 mediates alcoholinduced ciliary dysfunction. Sci Rep. 8(1):9701. doi: 10.1038/s41598-018-27924-x.

第556回 2018/7/25 Koen  
第557回 2018/7/31 岩野 Bo Wang, et al. (2018) Phospholipid Remodeling and Cholesterol Availability Regulate Intestinal Stemness and Tumorigenesis. Cell Stem Cell. 22(2):206-220.
第558回 2018/8/9 久冨 Chika Okimura, et al. (2018) Rotation of stress fibers as a single wheel in migrating fish keratocytes. Sci Rep. 8(1):10615. doi: 10.1038/s41598-018-28875-z.
第559回 2018/8/29 吉村 ①Jialing Zhang, et al. (2017) Nondestructive tissue analysis for ex vivo and in vivo cancer diagnosis using a handheld mass spectrometry system. Sci Transl Med. 9(406). pii: eaan3968. doi: 10.1126/scitranslmed.aan3968.

②Hannah Marie Brown,Valentina Pirro, and R. Graham Cooks (2018) From DESI to the MasSpec Pen: Ambient Ionization Mass Spectrometry for Tissue Analysis and Intrasurgical Cancer Diagnosis. Clin Chem. 64(4):628-630.

第560回 2018/9/4 成田  Domenico F. Galati, et al. (2018) Trisomy 21 Represses Cilia Formation and Function. Dev Cell. 46(5):641-650.
第561回 2018/9/18 竹田  Per Kristian Eide , et al. (2018) Magnetic resonance imaging provides evidence of glymphatic drainage from human brain to cervical lymph nodes. Sci Rep. 8(1):7194. doi: 10.1038/s41598-018-25666-4.
第562回 2018/9/25  Rui Song, et al. (2014) miR-34/449 miRNAs are required formotile ciliogenesis by repressing cp110. Nature. 510(7503):115-20.
第563回 2018/10/2 社本  Simon Schimmack, et al. (2016) Epithelial to Stromal Re-Distribution of Primary Cilia during Pancreatic Carcinogenesis. PLoS One. 11(10):e0164231. doi: 10.1371/journal.pone.0164231. eCollection 2016.
第564回 2018/10/23 久冨  Muhammad Myn Uddin, et al. (2017) Foxn1-b5t transcriptional axis controls CD8t T-cell production in the thymus. Nat Commun. 8:14419. doi: 10.1038/ncomms14419.
第565回 2018/10/30 岩野  Marco Seehawer, et al. (2018) Necroptosis microenvironment directs lineage commitment in liver cancer. Nature. 562(7725):69-75.
第566回 2018/11/06 吉村 Teresa W.M. Fan, et al. (2018) Exosomal lipids for classifying early and late stage non-small cell lung cancer. Anal Chim Acta. 1037:256-264. 
第567回 2018/11/14 成田 Fabien B. Wagner, et al. (2018) Targeted neurotechnology restores walking in humans with spinal cord injury. Nature. 563(7729):65-71. 
第568回 2018/11/20 竹田 ①Xue Yuan, et al. (2014) Deletion of IFT20 in early stage T lymphocyte differentiation inhibits the development of collagen-induced arthritis. Bone Res. 2:14038.

②AMY MAXMEN (2018) Self-driving car dilemmas reveal that moral choices are not universal. Nature. 562(7728):469-470. 

第569回 2018/11/27 Eszter K Vladar, et al. (2018) Cyclin-dependent kinase control of motile ciliogenesis. Elife. 7. pii: e36375. 
第570回 2018/12/5 社本 ①Ramandeep Singh et al. (2018)I Deep learning in chest radiography: Detection of findings and presence of change. PLoS One. 13(10):e0204155.

②Eirini Arvaniti et al. (2018) Automated Gleason grading of prostate cancer tissue microarrays via deep learning. Sci Rep. 8(1):12054. 

第571回 2018/12/11 久冨 Humberto Mestre et al. (2018) Flow of cerebrospinal fluid is driven by arterial pulsations and is reduced in hypertension. Nat Commun. 9(1):4878. 
第572回 2018/12/18 岩野 Ming-Hsiang Lee et al. (2018) Somatic APP gene recombination in Alzheimer’s disease and normal neurons. Nature. 563(7733):639-645. 
第573回 2018/12/26 吉村  ①Raquel González de Vega et al. (2018) MMP-11 as a biomarker for metastatic breast cancer by immunohistochemical-assisted imaging mass spectrometry. Anal Bioanal Chem. Sep 15. doi: 10.1007/s00216-018-1365-3

②Andreia M. Porcari et al. (2018) Multicenter Study Using Desorption-Electrospray-Ionization-Mass-Spectrometry Imaging for Breast-Cancer Diagnosis. Anal Chem. 90(19):11324-11332.